Polymeric micelles, nanogels, nanoparticles, cyclodextrins and hybrid metal (gold, silver) -polymer systems with solubilizing and stabilizing capacity of active substances, sensitive to stimuli, targetable, for the delivery of drugs, gene material, or growth factors.
Gelling systems responsive to stimuli, poly(pseudo)rotaxane-like supramolecular cyclodextrin complexes… to prepare depot systems and syringeable implants.
Stimuli-responsive polymer networks (micro/macro), materials with molecular recognition capacity, molecular imprinting, contact lenses for ocular drug release.
Engineering of novel aerogel designs and formats, bio-based aerogels as drug carriers for oral and pulmonary delivery, aerogels for wound healing, electroactive aerogels for tissue engineering.
Injectable systems, electrospun fibers, 2D and 3D printed architectures, porous frameworks obtained by supercritical CO2 techniques.
Micro and nanometric coatings with polymers and enzymes, sensitive to stimuli, with specific recognition capacity, ... for localized release of active substances, antibiofilm surfaces, drug-device combination products.
Physico-chemical and microstructural (texture, pore interconnectivity) characterization, mechanical and rheological properties of liquids, semisolids and solids, evaluation of excipients functionality, stability studies
Tablets, pellets, 3D printed dosage forms (printlets)
Electrospinning, electrospraying, 2D printing, particles obtained from gas-saturated solutions (PGSS), 3D printing.
Supercritical impregnation/extraction of bioactive agents, supercritical drying of gels, production of polymeric microparticles, sintering of polymeric structures, surface modification of nanoparticles
Use of Artificial Neural Networks, Fuzzy Logic, Genetic Algorithms or Gene Expression Programming (Artificial Neural Networks, fuzzy logic, genetic algorithms, GEP) in the design of pharmaceutical systems: extraction of information from big data, establishment of the design space of pharmaceutical systems, optimization of production processes, industrial scaling procedures.
MTT, LDH, WST-1, HET-CAM, in ovo tests, corneal permeability and opacity…